Canadian researchers have identified a new protein in the progression of breast cancer. According to a recent study published in the Journal of Biological Chemistry, the protein ARF1 plays a critical role in cancer cell growth and the spread of tumors. Targeting this protein with drug therapy may provide hope to women with breast cancer.
Combining a compound known as a gallium corrole with a protein carrier results in a targeted cancer therapy that is able to detect and eliminate tumors in mice with seemingly fewer side effects than other breast-cancer treatments, according to new research.
Scientists have revealed how a cancer causing protein is regulated by reactive oxygen species -- a type of stress signal. Their findings provide new insight into how this protein normally behaves in human cells and may help in the design of drugs targeting specific cancers.
Researchers have reported a discovery that could help scientists develop drugs to fight the much-feared bird flu and other virulent strains of influenza. They have determined the three-dimensional structure of a site on an influenza A virus protein that binds to one of its human protein targets, thereby suppressing a person's natural defenses to the infection and paving the way for the virus to replicate efficiently.
New research suggests that blocking the activity of a protein in the blood could offer powerful protection against some skin cancers. In the study, normal mice and mice that had a genetically engineered protein deficiency were exposed to almost a year of ultraviolet light that mimics chronic sun exposure.
Researchers at the University of Pennsylvania School of Medicine have found that some proteins of the immune system can promote tumor growth. Investigators found that instead of fighting tumors, the protein C5a, which is produced during an immune response to a developing tumor, helps tumors build molecular shields against T-cell attack.
Researchers have identified a protein likely responsible for causing breast cancer to spread. Metastatic cancer occurs when cancer cells from the original tumor travel to distant sites via the blood system.
In a biological rendition of fiction's Strange Case of Dr. Jekyll and Mr. Hyde, researchers have found that a protein thought to protect against cancer development can actually spur the spread of tumors.
Scientists have discovered a new protein in the inner membrane of the cell nucleus. This protein may play an important role in cell division and now provides a new piece of the puzzle to study in cancer research.
The mainstay immune system protein TRAF6 plays an unexpected, key role activating a cell signaling molecule that in mutant form is associated with cancer growth, researchers report.